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Chloroquine diphosphate, also referred to as chloroquine phosphate, is a 4-aminoquinoline antimalarial medicine. It can prevent the nucleic acid synthesis of Plasmodium schizonts, disrupt the growth and recreation of Plasmodium, and has a high-efficiency murder impact on Plasmodium schizonts.
is a substrate of MRP in multidrug-resistant cell lines and inhibits photoaffinity labeling of MRP by the quinoline-based photoactive drug IAAQ.
This product is white crystalline powder, odorless and bitter in taste. When exposed to light, the color changes, and the aqueous solution exhibits an acidic reaction. Soluble in water, almost insoluble in ethanol, chloroform and ether.
Oral administration of chloroquine diphosphate is fast and sufficient, with slow excretion and metabolism, long-lasting effect and low toxicity. Also has anti-tissue enamoeba effects.
The latest research shows that chloroquine diphosphate has a certain inhibitory effect on the new coronavirus pneumonia (COVID-19).